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The Engagement Gap

Patient adoption of diagnostic tests and adherence to treatment protocols is suboptimal.

50.3%of women who meet hereditary-testing criteria and are offered a test opt in.
$1B/yrpain point
Brabender, Ann Surg Oncol 2025
64.8%of non-diabetic patients discontinue GLP-1 therapy within one year.
$30B/yrpain point
Rodriguez, JAMA Netw Open 2025
45%of patients decline a clinical trial when they are offered one.
$6B/yrpain point
Unger, JNCI 2021 · 35 studies, 9,759 patients

These findings – across diagnostic testing, treatment adherence, and clinical testing – reflect moments where eligible patients do not start, complete, or continue to the next relevant step of care. Citrus has the power to change that. The broader opportunity in the Life Sciences and Diagnostics market, including these examples, roughly totals $50B.

Where Citrus Creates Lift

Improvements compound at the interaction moment.

Below are moments where socially intelligent interaction can improve the odds of follow-through. Citrus applies interactive interpretability, rapport, and adaptive steering where even modest changes can benefit the business.

Offer Refusal

A patient is eligible and offered a test or program.

Without CitrusThe explanation does not resolve hesitation, so the patient declines.
With CitrusInterpretationdetects uncertainty in the moment.Steeringadapts the explanation, so the patient is more likely to understand and opt in.

Multi-Step Task Drop-Off

The patient must complete several steps outside the clinic.

Without CitrusThe patient loses momentum between consent, collection, scheduling, or return steps.
With CitrusRapportmaintains continuity across steps.Steeringre-orients the patient toward the next concrete action.

Follow-Up Decay

A patient receives a result or next-step recommendation.

Without CitrusFollow-up feels generic or poorly timed, so the patient delays, disengages, or declines.
With CitrusInterpretationreads engagement signals.Steeringadapts timing, tone, and context to improve the chance of re-engagement.

Early Discontinuation

A patient starts treatment and encounters side effects or declining motivation.

Without CitrusConcerns are not noticed early enough, so the patient stops.
With CitrusInterpretationsurfaces friction earlier.Rapportaddresses concerns.Steeringroutes the patient toward support if necessary.
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